Journal of Harmonized Research in Pharmacy

EFFECT OF DIFFERENT TABLET DISNTEGRANTS ON PROCHLORPERAZINE MALEATE TABLETS

Abstract

Author(s): Kuldeep Ganju, Eisha Ganju

The study is performed to determine the effect of selected superdisintegrants, Primellose and Primojel, on the Disintegration time (DT) of tablets of Prochlorperazine maleate. The molecule is an anti emetic and a high rate of disintegration would give faster pharmacological effect. 1%, 2% and 4% concentrations of the selected disintegrants were added and all other composites were kept constant. 4% Primellose gave the best result with a DT of 1 min 45 s.