Journal of Harmonized Research in Pharmacy

HYBRIDOMA TECHNOLOGY: A REVIEW

Abstract

Author(s): Sunita Sharma

Hybridoma innovation is the strategy in which expansive amount of indistinguishable antibodies are delivered which are otherwise called monoclonal antibodies. It is finished by the organization of an tigen in mouse which creates a resistant reaction. The B-cells creating antibodies are then reaped from the infused mouse. The gathered B-cells are then melded with B malignancy cells which stay undying. This produces cross breed cell line called hybridoma which has the neutralizer creating capacity of the B-cell. The hybridomas can be developed in culture with one suitable cell which produces societies having hereditarily indistinguishable hybridomas. It produces monoclonal antibodies. It holds the capacity to develop in tissue culture and don't have counter acting agent delivering ability. Keywords: B-cells, Hybridoma, Monoclonal antibodies