Author(s): Richa. A. Dayaramani, Paresh U Patel
A validated RP-HPLC analytical method has been developed for the simultaneous estimation of Didanosine and Stavudine in bulk and in a synthetic mixture prepared in the laboratory. The proposed method is fast, simple, accurate, precise, specific, and has ability to separate drug from excipients if found in formulation if developed in future. The method is suitable for routine simultaneous analysis of Didanosine and Stavudine. The method can be successfully applied in simultaneous analyses of the two drugs in case of extensive clinical trials. The simplicity of the method allows for application in laboratories that lack sophisticated analytical instruments such as LC–MS. The proposed method requires no sample pre treatment and is quite economical for routine analyses.
Journal of Harmonized Research in Pharmacy received 119 citations as per google scholar report