Author(s): Vivek Gupta*, A. Pandurangan
4-acetamidophenoxyacetylhydrazide is synthesized from paracetamol which on reaction with various aldehyde gives Schiff bases. Schiff bases treated with mercaptoaceticacid to produce thiazolidinenone derivatives. The entire synthesized compound characterized by physical and analytical data. The chemical structures of synthesized compound were confirmed by means of IR, 1HNMR and MS. Antimicrobial activity of synthesized compounds evaluated by cup-plate method. Synthesized compound showed good antimicrobial activity.